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Oxidative Stress in Fibromyalgia
I was invited to share the following blog post on oxidative stress as it related to fibromyalgia. The original post can be found at http://robinthomas.biz I plan to continue this series, taken from a recent webcast. If anyone would like to hear the entire webcast, contact me and I will be able to send an MP3 file. Robin
In my recent teleseminar with Cynda Crawford about Fibromyalgia and Chronic Fatigue Syndrome, I discussed oxidative stress in Fibromyalgia and Chronic Fatigue Syndrome. I want to share some of that discussion with my readers.
In one of Dr. Strand’s studies, this patient’s complaints underline many of the typical symptoms in fibromyalgia patients.
“For a year or more I had chills, a stiff neck that came and went. Almost constant ear pain, with a number of ear infections and tiredness. Sensitivity to cold which eventually became painful to my muscles, irritable bowel, water retention, mental fog, & bruising, nightly sleep disruption. I felt drained of all energy constantly. Getting 10 – 12 hours sleep at night and 3 – 6 hour naps was never enough. This would not give me back the energy level that I was so used to. The almost daily 40 minute walks never energized me; I just felt more drained.”
Fibromyalgia is a chronic condition that causes widespread pain in muscles, tendons, and ligaments. The main symptoms are a dull, aching pain throughout the body; chronic fatigue; and tender points on both sides of the body, above and below the waist.
People also suffer from sleep problems and disorders: from a feeling of exhaustion regardless of the amount of daily sleep to experiencing co-existing conditions, like restless legs syndrome and sleep apnea. Studies show that fibromyalgia sufferers do not experience deep, restorative sleep. In addition to overall muscle pain, people also experience increased pain in certain body parts, such as:
- the back of the head
- between the shoulder blades
- top of the shoulders
- front sides of the neck
- upper chest
- outer elbows
- upper part and side of the hips
- the inner knees
Medical literature shows there is usually one of three different events that can trigger fibromyalgia or chronic fatigue.
- serious illness, such as chronic infections or other prolonged illness.
- physical injury or trauma to your body, particularly to the neck and head area.
- severe or prolonged emotional stress.
Typically, it can be a combination of any of these factors. All three events significantly increase the number of free radicals you produce and can certainly lead to oxidative stress.
Clinical studies support that patients diagnosed with fibromyalgia have significantly lower antioxidative status as compared to those in a control group.
In 2009 and 2010, new studies from Turkey and Spain are corroborating the relationship between oxidative stress and the multiple symptoms of fibromyalgia, including pain. Other studies at Vanderbilt were inconclusive, though they did show a significant correlation with oxidative stress and fatigue.
The research on oxidative stress is important to consider when discussing the chronic conditions of fibromyalgia and chronic fatigue syndrome. In my next post, I’ll explain oxidative stress in more detail.
Information for this article was taken from a number of sources:
Redox Rep. 2006 Altindag O, Celik H;11(3):131-5. Department of Physical Medicine and Rehabilitation, Harran University, Sanliurfa,Turkey. Total antioxidant capacity and the severity of the pain in patients with fibromyalgia.
Clin Rheumatol. 2009 Apr;28(4):435-8. Epub 2008 Dec 17. Chung CP, Titova D, Oeser A, Randels M, Avalos I, Milne GL, Morrow JD, Stein CM Department of Medicine, School of Medicine, Vanderbilt University, Nashville, TN 37232-6602, USA. Oxidative stress in fibromyalgia and its relationship to symptoms.
Stress. 2010 Jul 28. [Epub ahead of print] Nazıroğlu M, Akkuş S, Soyupek F, Yalman K, Celik O, Eriş S, Uslusoy GA. Department of Biophysics, Medical Faculty, Suleyman Demirel University, Isparta, Vitamins C and E treatment combined with exercise modulates oxidative stress markers in blood of patients with fibromyalgia: A controlled clinical pilot study.
Robin started contributing to Lumigrate in August 2010. "Meet Robin Thomas", a topic in our biographies/vitae forum is at http://www.lumigrate.com/forum/meet-robin-thomas to read all about her journey, which was greatly influenced by the need to help solve her youngest son's significant health challenges. For those who want just the overview here: After working over 22 years in medical research at the University of North Carolina on chronic inflammatory diseases she switched her focus to preventive health in 2004 when she was introduced to USANA Health Sciences. Robin is passionate about helping others improve their health, have more energy, manage their weight, and improve their skin.
I love meeting new friends !
"I dream of a world free from pain and suffering. I dream of a world free from disease. The USANA family will be the healthiest family on earth. Share my vision. Love life and live it to its fullest in happiness and health."
-Dr. Myron Wentz, Founder and Chairman, USANA Health Sciences
This forum is provided to allow members of Lumigrate to share information and ideas. Any recommendations made by forum members regarding medical treatments, medications, or procedures are not endorsed by Lumigrate or practitioners who serve as Lumigrate's medical experts.