Cause / Effect Worthy of Examination with Lyme Borreliosis and Mental and Behavioral Function / "State"

Which came first, the chicken or the egg? You will see, below, that there's an important reference to the application of this analogy to behavioral / mental health and the underlying cause or causes and contributors to these issues. They point out, as you will see, below: 

As both patients and doctors are struggling with the confusion about the psychiatric expression of Lyme Borreliosis and with the reversal of the causal effect ("is the mental state the cause of the disease or rather a symptom?"), we included this list for you. It may be helpful, for example in dealing with accusations of Child Protective Services.

Credit due to Claus-Peter Kessler, MD, and long-time Facebook friend and recent Lumigrate contributor relative to his specialty niche of viewing the many contributors to health or lack thereof through the lens of a unique testing method for determining underlying issues that interplay with Lyme, mold, chemicals and so on, while teaching to avoid / eliminate exposure to any elements a person, dog, cat, and so on might be sensitive to. 

He had posted this on Facebook on September 10, 2017 with a note to see his note on Facebook about Lyme and mercury.  Here's what I've provided on Lumigrate about that at the following link, it's a comment under the initial topic about Dr. Kessler and his methods which states:

Patients with Lyme disease: Most therapies just focus on the symptoms and fight the spirochetes without involving the order of the system of your body.

None of you had been screened for disturbing foci, mercury-sensitivity, aluminum-sensitivity, a dental focus or maybe a disturbing scar (tonsil), which influences the order of your system and the capability of the body to respond to therapy. This means, that you will have a different outcome because the information (energy, medications)  they are giving you might not get where it is needed.

The order of the system of a mercury-sensitive person (ApoE4), what most chronic Lyme patients are, is disturbed by chronic, daily exposure with traces of mercury by ingestion, inhalation and skin penetration.

The infection with Borrelia can not be correctly counteracted and fought by the disturbed immune system, and the burden of the Borrelia infection and the unknowing new daily exposure of mercury weakens the body even further.

Medicine wants to add information -- antibiotics, supplements etc., and find pathological, biochemical changes of the disorder, but the information is not carried to the place where it is needed because the body is in a dysautonomic state -- it is out of order -- and even more highly weakened by those invaders (they even have electron microscopic pictures of).

It is like: You want to put tiles on a wall (treat Lyme) and someone is using a sledgehammer (mercury exposure) next door. It makes no sense in adding more and stronger glue (antibiotics, supplements); you have to stop the vibration of the sledgehammer first to be able to work in a field, which then is not disturbed.

The flair ups of the disease can only be explained by the incidence and level of new mercury exposure, because the level of borrelia is not changed from one hour to the next, like the symptoms change. All patients feel better with chelation, as long as the chelator doesn't contain traces of mercury, and if the exposure is stopped or drastically reduced. For possible sources of mercury read what's at comment #1, above (at this link if you wish to take a link: www.lumigrate.com/forum/claus-peter-kessler-md-facebook-learn-test-order-system-disrupted-his-mantra#comment-2956 [1])

Herxheimer reaction is a dysautonomic reaction to acute mercury exposure (inhalation, ingestion or transdermal), it has nothing to do with release of toxins from killed spirochetes. It is a postulate by Dr Herxheimer, not a proven fact, yet everyone takes it for granted as he postulated.

If a factory is not organized and controlled, it doesn't work.

Bring your system back in order, so that it helps to fight the disease.

That is why I teach my patients how to test for the ingredients they are sensitive to, in each item they like to ingest, inhale or put on their skin.

 

www.lumigrate.com/forum/claus-peter-kessler-md-facebook-learn-test-order-system-disrupted-his-mantra#comment-2964 [2]

 

Bolding added by me, as I frequently do for the Lumigrate YOUsers.

---

From Dr. Richard Horowitz -
"Horowitz Multiple Systemic Infectious Disease Syndrome Questionnaire for Suspected Lyme Disease" — (HMQ = Horowitz MSIDS Questionnaire).

Patients who present with neuropsychiatric symptoms with multisystemic physical complaints may have been exposed to Lyme and associated tick-borne diseases.

Dr Robert Bransfield, a well known Lyme literate psychiatrist, has published on the relationship between microbes, infections and mental illness. He presented to the NY State Senate last week via video link about that relationship.

I recently spoken with Senator Serino and local Assemblywoman Didi Barrett (strong supporters of the Lyme community) about adopting broader use of the HMQ as a screening tool among different health care professionals. The HMQ is an inexpensive, validated screening tool which could be given to clients while they are in the waiting room.

This would help mental health professional to help determine whether tick-borne diseases may be at the origin of their psychiatric problems, or worsening their underlying conditions.

A broader goal would be to get health care practitioners in different sub specialties to administer the HMQ to groups of patients with chronic diseases mimicking Lyme, and determine whether tick-borne disease may be causing disabling symptoms and increasing health care costs.

This is important, as we have oftentimes witnessed Lyme, Bartonella and Babesia as well as other co-infections increasing the severity of symptoms. Many patients improve their physical and neuropsychiatric symptoms once Lyme and associated co-infections are treated, so there is hope for those affected.

Here are a list of scientific references put together by Dr Bransfield, linking tick-borne diseases to a broad range of psychiatric illnesses.

---

The list is found at the article that Dr. Kessler had shared on Facebook with this, while also suggesting people go to his Notes section of his profile and read the note he provided about Lyme.  I'm providing the link to the article and the brief content before the list, plus what is in the list for A, for B-Z, please go and look. I chose to bring all the articles in the list that started with A because you can see what a wide range of things are being attributed to Lyme... JUST with the articles that start with 1/26th of the alphabet. 

Titled List of references for psychiatric symptoms of Lyme Disease and provided at the OnLyme dog org website the link is: 

on-lyme.org/en/sufferers/lyme-stories/item/264-list-of-references-for-psychiatric-symptoms-of-lyme-disease [3]     and the beginning information to get you going (and please keep going and take the link for all of it and seeing the whole website and explore, is: (bolding some more paragraph breaks added by me for YOUser's ease of reading.... )

List of references for psychiatric symptoms of Lyme Disease
Written by    Huib

This extensive list of peer-reviewed references demonstrating the association between Lyme Borreliosis, co-infections and psychiatric symptoms was provided by Robert C Bransfield, MD, DLFAPA, to the New York Senate after the recent hearing on Lyme Disease.

As both patients and doctors are struggling with the confusion about the psychiatric expression of Lyme Borreliosis and with the reversal of the causal effect ("is the mental state the cause of the disease or rather a symptom?"), we included this list for you. It may be helpful, for example in dealing with accusations of Child Protective Services.

Introduction

There are several thousand peer-reviewed references demonstrating the association between infections and mental symptoms and at least 65 different microbes have been recognized as causing mental symptoms. Over three hundred peer-reviewed articles describe the causal association between Lyme/tick-borne diseases and mental symptoms, pathophysiology, morbidity and mortality some of which are included in the attached addendum.

Lyme disease: a neuropsychiatric illness is a major and classic article summarizing this association. A Controlled Study of Cognitive Deficits in Children With Chronic Lyme Disease is a particularly useful resource for describing some of the cognitive symptoms associated with Lyme/tick-borne diseases.

Attempted suicide and completed suicide associated with neuropsychiatric manifestations of Lyme disease and other tick-borne disease has been observed and reported by the author and many other clinicians.

An article in the American Journal of Psychiatry, Higher Prevalence of Antibodies to Borrelia Burgdorferi in Psychiatric Patients Than in Healthy Subjects compared 499 psychiatric inpatients to matched pair healthy controls and found significantly more psychiatric patients were seropositive for Borrelia burgdorferi (33% vs. 19%), thereby demonstrating an association between Borrelia burgdorferi infections and psychiatric morbidity. In contrast, there are only a few poor quality articles that attempt to negate the causal association between tick-borne diseases and psychiatric illness that lack scientific merit.

Within these articles there is significant evidence that more extensive antibiotic treatment is needed to control the psychiatric symptoms associated with Lyme disease and other tick-borne diseases.

Peer-Reviewed References for Psychiatric Symptoms
 and Lyme/Tick-Borne Diseases

A controlled study of deficits in children with chronic Lyme disease. AUTHORS: Tager, F., Fallon, B., Keilp, J, Rissenberg, M., Jones, C.R. & Liebowitz, M. SOURCE: Journal of Neuropsychiatry and Clinical Neurosciences, 2001; 13: 500-507.

Acute disseminated encephalomyelitis [letter] 
AUTHORS: Fallon BA, Nields JA. 
SOURCE: J Neuropsychiatry Clin Neurosci 1998 Summer;10(3):366-7

Acute and Chronic Lyme Disease: Controversies for Neuropsychiatry. AUTHORS: Hurley RA, Taber KH. SOURCE: J Neuropsychiatry Clin Neurosci 20:1, Winter 2008 http://neuro.psychiatryonline.org [4]

Acute and chronic pain associated with Lyme borreliosis: clinical characteristics and pathophysiologic mechanisms. AUTHORS: Zimering JH, Williams MR, Eiras ME, Fallon BA, Logigian EL, Dworkin RH et al. SOURCE: Pain. 2014 Aug;155(8):1435-1438.

Acute and chronic neuroborreliosis with and without CNS involvement: a clinical, MRI, and HLA study of 27 cases. AUTHORS: Krüger H, Heim E, Schuknecht B, Scholz S. SOURCE: J Neurol. 1991 Aug;238(5):271-80.

Acute Lyme Neuroborreliosis With Transient Hemiparesis and Aphasia. AUTHORS: Sokolov A, Lienhard R, Du Pasquier R, Véronique Erard V. SOURCE: Annals of Emergency Medicine. Published Online: February 25, 2015 http://www.annemergmed.com/article/S0196-0644(15)00028-1/abstract

A Girl with Seizures. AUTHOR: Carla Rothaus. SOURCE: NEJM. May 22nd, 2015. http://blogs.nejm.org/now/index.php/a-girl-with-seizures/201... [5]

A Groundhog, a Novel Bartonella Sequence, and My Father’s Death. AUTHORS: Breitschwerdt EB, Maggi RG, Cadenas MB, Vissotto de Paiva Diniz PP. SOURCE: Emerging Infectious Diseases • www.cdc.gov/eid [6] • 2009 Aug;15(12): 2080-6 http://www.cdc.gov/eid/content/15/12/pdfs/2080.pdf [7]

Alcohol and epilepsy: a case report between alcohol withdrawal seizures and neuroborreliosis. AUTHORS: Gheorghiev C, De Montleau F, Defuentes G. SOURCE: Encephale. 2011 Jun;37(3):231-7.

Altered mental status, an unusual manifestation of early disseminated Lyme disease: A case report. AUTHORS: Chabria SB, Lawrason J. SOURCE: J Med Case Reports. 2007 Aug 9;1:62.

Alzheimer's disease and infection: Do infectious agents contribute to progression of Alzheimer's disease? AUTHORS: Honjo K, van Reekum R, Rand Nicolaas, Verhoeff NPLG. SOURCE: Alzheimer's and Dementia. Vol 5;4, July 2009, p 348-360

Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria. AUTHOR: Miklossy J. SOURCE: J Neuroinflammation. 2011 Aug 4;8(1):90. [Epub ahead of print]

Alzheimer Disease: a novel hypothesis integrating spirochetes, biofilm, and the immune system. AUTHORS: Allen HB, Morales D, Jones K, Joshi S. SOURCE: Journal of Neuroinfectious Diseases. http://www.omicsonline.com/open-access/neuroinfectious-disea... [8]

Alzheimer's disease Braak Stage progressions: reexamined and redefined as Borrelia infection transmission through neural circuits. AUTHOR: MacDonald AB. SOURCE: Med Hypotheses. 2007;68(5):1059-64. Epub 2006 Nov 17.

Alzheimer's neuroborreliosis with trans-synaptic spread of infection and neurofibrillary tangles derived from intraneuronal spirochetes. AUTHOR: MacDonald AB. SOURCE: Med Hypotheses. 2007;68(4):822-5. Epub 2006 Oct 20.

Antibodies against OspA epitopes of Borrelia burgdorferi cross-react with neural tissue. AUTHORS: Alaedini A, Latov N. SOURCE: J Neuroimmunol. 2005 Feb;159(1-2):192-5. Epub 2004 Nov 26.

Anti-neural antibody reactivity in patients with a history of Lyme borreliosis and persistent symptoms. AUTHORS: Stricker RB, Johnson L. SOURCE: Brain, Behavior, and Immunity 24 (2010) 1025

Anti-neural antibody reactivity in patients with a history of Lyme borreliosis and persistent symptoms. AUTHORS: Volkman D. SOURCE: Brain, Behavior, and Immunity 24 (2010)

A Review of Death Certificates Listing Lyme Disease as a Cause of Death in the United States. AUTHORS: Kugeler KJ, Griffith KS, Gould LH et al.  SOURCE: Clin Infect Dis. (2011) 52 (3), 364-367. doi: 10.1093/cid/ciq157. http://cid.oxfordjournals.org/content/52/3/364.full.pdf  [9] http://cid.oxfordjournals.org/content/52/3/364.long [10]

The association between tick-borne infections, Lyme borreliosis and autism spectrum disorders 
AUTHORS: Bransfield RC, Wulfman JS, Harvey WT, Usman AI.
SOURCE: Medical Hypotheses. 5 Nov 2007

Association of Lyme Disease and Schizoaffective Disorder, Bipolar Type: Is it Inflammation Mediated? AUTHORS: Mattingley DW, Koola MM. SOURCE: Indian J Psychol Med. 2015 Apr-Jun;37(2):243-6.

Audiologic manifestations of patients with post-treatment Lyme disease syndrome 
AUTHORS: Shotland LI, Mastrioanni MA, Choo DL, Szymko-Bennett YM, Dally LG, Pikus AT, Sledjeski K, Marques A 
SOURCE: Ear Hear. 2003 Dec;24(6):508-17

Autism and Lyme Disease AUTHORS: Robert C. Bransfield, MD, Mason Kuhn, MS. SOURCE: JAMA. 2013;310(8):856 doi:10.1001/jama.2013.194747

A woman in her 50s with manic psychosis. AUTHORS: Pasareanu AR, Mygland Å, Kristensen Ø. SOURCE: Tidsskr Nor Laegeforen. 2012 Mar 6;132(5):537-9

---